Researchers from North Carolina State University (USA) have developed a technology to be applied to the polymer film implants for reducing the risk of rejection by the body. This was reported on the website of the educational institution.

The basis was the coating polymer polyetheretherketone (PEEK), coupled to hydroxyapatite (HA) – main inorganic component of bone. Hydroxyapatite coated onto a thin layer of zirconia stabilized with yttria (YSZ), and then heated using microwaves. YSZ while performing the role of the screen, to prevent melting of the PEEK. Heating HA made more resistant to the body’s internal environment, slowing down the process of dissolution of calcium phosphate and promoting the adoption of the implant.

In the experiment, the researchers tested three models PEEK-implants in rabbits: no cover; coated with HA, treated with microwaves; coated with HA, and treated with microwaves in an autoclave – a component for enhancing the crystal structure. Microscopic examination and X-rays performed after eighteen weeks after surgery showed that bone formation around the implant with HA coating of more than twice the rate PEEK-uncoated implants.

To confirm the results of researchers conducted a push-testing for the amount of force required to separate the implant from the bone model. In the case of implants HA, treated with microwaves rate was 299.1 Newton per square millimeter, implants HA, treated in autoclave – 312.5 Newton per square millimeter. Branch uncovered PEEK-implants require 183.9 newtons per square millimeter.

“Regardless of the growth rate and the viscosity of the bone samples with HA-coated PEEK-surpassed the original implants. Probably, their production will lead to a slight rise in price of the procedure, but will minimize the need for repeated operations “, – said professor Afsaneh Rabiey.

Furthermore, to date recorded side effects from the use of modified implants. Management on sanitary inspection by the Food and Drug Administration (FDA) of the USA has approved the technology for use in clinical practice. Currently, scientists are searching for partners for commercialization.

Naked Science